Michael J. MooreAssistant Professor of Biomedical Engineering Email: mooremj@tulane.edu 523 Lindy Boggs Building |
University of Nebraska, Lincoln NE, 1999 B.S. Biological Systems Engineering
Mayo Clinic College of Medicine, Rochester MN, 2005 Ph.D. Biomedical Engineering
Massachusetts Institute of Technology, Cambridge MA, and
The Schepens Eye Research Institute, Harvard Medical School, Boston MA, 2007 Post-doc
Our group utilizes tissue engineering and related technologies for the study of central nervous system (CNS) regeneration and development of treatments for CNS disorders. In particular, we are interested in the relationship between the three dimensional architecture of regenerating CNS tissue and its functionality. The major experimental goals in our laboratory are to: 1) design and fabricate biomaterial constructs with specified structural and molecular microarchitectures and employ 3D tissue culture preparations and 3D microscopic imaging for evaluation of constructs; 2) design and evaluate drug delivery systems for promotion of CNS axon regeneration; 3) develop implantable materials for CNS tissue engineering and evaluation in small mammals.
Ruth L. Kirschstein National Research Service Award (National Institutes of Health) 2003-2005
George PM, Saigal R, Lawlor D, Moore MJ, LaVan DA, Marini R, Selig M, Makhni M, Burdick JA, Langer RS, Kohane DS. Stand-alone three-dimensional conductive constructs for nerve regeneration and other applications. Biomaterials, submitted.
de Ruiter CGW, Onyeneho IA, Liang ET, Moore MJ, Malessy MJA, Spinner RJ, Lu L, Currier BL, Yaszemski MJ, Windebank AJ. Methods for in vitro characterization of multichannel nerve tubes. J Biomed Mater Res, in press.
Moore MJ, Friedman JA, Lewellyn EB, Mantila SM, Krych AJ, Knight AM, Lu L, Currier BL, Spinner RJ, Marsh RW, Windebank AJ, Yaszemski MJ. Multiple-channel scaffolds to promote spinal cord axon regeneration. Biomaterials, 27(3):419-29, 2006.
Moore MJ, Jabbari E, Ritman EL, Lu L, Currier BL, Windebank AJ, Yaszemski MJ. Quantitative analysis of interconnectivity of porous biodegradable scaffolds with micro-CT. J Biomed Mater Res 71A(2):258-67, 2004.
Talac R, Friedman JA, Moore MJ, Lu L, Jabbari E, Windebank AJ, Currier BL, Yaszemski MJ. Animal models for tissue engineering approaches to spinal cord injury. Biomaterials 25(9), Special Edition on Animal Models for Tissue Engineering: 1505-10, 2004.
Friedman JA, Windebank AJ, Moore MJ, Spinner RJ, Currier BL, Yaszemski MJ. Biodegradable polymer grafts for surgical repair of the injured spinal cord. Neurosurgery 51(3):742-52, 2002.
Gill JS, Zhu X, Moore MJ, Lu L, Yaszemski MJ, Windebank AJ. Effects of NFkB decoy oligonucleotides released from biodegradable polymer microparticles on a glioblastoma cell line. Biomaterials 23(13):2773-81, 2002.
